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Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain

BACKGROUND: Intrauterine growth restriction (IUGR) is a common complication of pregnancy and is associated with significant neurological deficits in infants, including white matter damage. Previous work using an animal model of IUGR has demonstrated that IUGR rats exhibit neurobehavioral deficits an...

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Detalhes bibliográficos
Publicado no:J Neurodev Disord
Main Authors: Zanno, Allison E., Romer, Micah A., Fox, Lauren, Golden, Thea, Jaeckle-Santos, Lane, Simmons, Rebecca A., Grinspan, Judith B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913005/
https://ncbi.nlm.nih.gov/pubmed/31839002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11689-019-9297-6
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