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Alternative Splicing of RAD6B and Not RAD6A Is Selectively Increased in Melanoma: Identification and Functional Characterization

Rad6B, a principal component of the translesion synthesis pathway, and activator of canonical Wnt signaling, plays an essential role in cutaneous melanoma development and progression. As Rad6 is encoded by two genes, namely, UBE2A (RAD6A) and UBE2B (RAD6B), in humans, we compared their expressions i...

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Bibliografski detalji
Izdano u:Cells
Glavni autori: Gajan, Ambikai, Martin, Carly E., Kim, Seongho, Joshi, Milap, Michelhaugh, Sharon K., Sloma, Ido, Mittal, Sandeep, Firestine, Steven, Shekhar, Malathy P. V.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912459/
https://ncbi.nlm.nih.gov/pubmed/31683936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111375
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