Alternative Splicing of RAD6B and Not RAD6A Is Selectively Increased in Melanoma: Identification and Functional Characterization

Rad6B, a principal component of the translesion synthesis pathway, and activator of canonical Wnt signaling, plays an essential role in cutaneous melanoma development and progression. As Rad6 is encoded by two genes, namely, UBE2A (RAD6A) and UBE2B (RAD6B), in humans, we compared their expressions i...

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Publicado no:Cells
Main Authors: Gajan, Ambikai, Martin, Carly E., Kim, Seongho, Joshi, Milap, Michelhaugh, Sharon K., Sloma, Ido, Mittal, Sandeep, Firestine, Steven, Shekhar, Malathy P. V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912459/
https://ncbi.nlm.nih.gov/pubmed/31683936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111375
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