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Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis

Cartilage loss is a central event in the pathogenesis of osteoarthritis (OA), though other than mechanical loading, the biochemical mechanisms underlying OA pathology remain poorly elucidated. We investigated the role of Pink1-mediated mitophagy in mitochondrial fission, a crucial process in OA path...

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Bibliografiske detaljer
Udgivet i:J Clin Med
Main Authors: Shin, Hyo Jung, Park, Hyewon, Shin, Nara, Kwon, Hyeok Hee, Yin, Yuhua, Hwang, Jeong-Ah, Song, Hee-Jung, Kim, Jinhyun, Kim, Dong Woon, Beom, Jaewon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912334/
https://ncbi.nlm.nih.gov/pubmed/31684073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8111849
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