p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common type of joint disease associated with cartilage breakdown. However, the role played by mitochondrial dysfunction in OA remains inadequately understood. Therefore, we investigated the role played by p66shc during oxidative damage and mitochondrial dy...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Shin, Hyo Jung, Park, Hyewon, Shin, Nara, Shin, Juhee, Gwon, Do Hyeong, Kwon, Hyeok Hee, Yin, Yuhua, Hwang, Jeong-Ah, Hong, Jinpyo, Heo, Jun Young, Kim, Cuk-Seong, Joo, Yongbum, Kim, Youngmo, Kim, Jinhyun, Beom, Jaewon, Kim, Dong Woon
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152540/
https://ncbi.nlm.nih.gov/pubmed/32308389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S234198
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