Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function

BACKGROUND: The giant sarcomere protein titin is important in both heart health and disease. Mutations in the gene encoding for titin, TTN, are the leading known cause of familial dilated cardiomyopathy. The uneven distribution of these mutations within TTN motivated us to seek a more complete under...

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Bibliographic Details
Published in:Circulation
Main Authors: Zaunbrecher, Rebecca J., Abel, Ashley N., Beussman, Kevin, Leonard, Andrea, von Frieling-Salewsky, Marion, Fields, Paul A., Pabon, Lil, Reinecke, Hans, Yang, Xiulan, Macadangdang, Jesse, Kim, Deok-Ho, Linke, Wolfgang A., Sniadecki, Nathan J., Regnier, Michael, Murry, Charles E.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911360/
https://ncbi.nlm.nih.gov/pubmed/31587567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.039521
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