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PAD-Beads enrichment enhances detection of PrP(Sc) using real-time quaking-induced conversion

OBJECTIVE: Scrapie is a transmissible spongiform encephalopathy (TSE) that naturally occurs in sheep and goats. This fatal neurodegenerative disease results from misfolding of the normal cellular prion protein (PrP(C)) to a pathogenic prion protein form (PrP(Sc)). This pathogenic form, PrP(Sc), accu...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Hwang, Soyoun, Dassanayake, Rohana P., Nicholson, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911270/
https://ncbi.nlm.nih.gov/pubmed/31836019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-019-4842-7
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