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Establishing quantitative real-time quaking-induced conversion (qRT-QuIC) for highly sensitive detection and quantification of PrP(Sc) in prion-infected tissues
BACKGROUND: PrP(Sc), the only known constituent of prions, the infectious agents causing prion diseases, can be detected by real-time quaking-induced conversion (RT-QuIC). However, there is no efficient method to quantify the amount of PrP(Sc) by RT-QuIC. RESULTS: Here we introduce quantitative RT-Q...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893511/ https://ncbi.nlm.nih.gov/pubmed/24252329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-44 |
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