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Predicting clinical decline and conversion to Alzheimer’s disease or dementia using novel Elecsys Aβ(1–42), pTau and tTau CSF immunoassays

We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1–42), tTau and...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Blennow, Kaj, Shaw, Leslie M., Stomrud, Erik, Mattsson, Niklas, Toledo, Jon B., Buck, Katharina, Wahl, Simone, Eichenlaub, Udo, Lifke, Valeria, Simon, Maryline, Trojanowski, John Q., Hansson, Oskar
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911086/
https://ncbi.nlm.nih.gov/pubmed/31836810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54204-z
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