Predicting clinical decline and conversion to Alzheimer’s disease or dementia using novel Elecsys Aβ(1–42), pTau and tTau CSF immunoassays

We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1–42), tTau and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Blennow, Kaj, Shaw, Leslie M., Stomrud, Erik, Mattsson, Niklas, Toledo, Jon B., Buck, Katharina, Wahl, Simone, Eichenlaub, Udo, Lifke, Valeria, Simon, Maryline, Trojanowski, John Q., Hansson, Oskar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911086/
https://ncbi.nlm.nih.gov/pubmed/31836810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54204-z
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