CSF biomarkers of Alzheimer’s disease concord with amyloid-β PETand predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

INTRODUCTION: We studied whether fully automated Elecsys cerebrospinal fluid (CSF) immunoassay results were concordant with positron emission tomography (PET) and predicted clinical progression, even with cutoffs established in an independent cohort. METHODS: Cutoffs for Elecsys amyloid-β(1–42) (Aβ)...

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Udgivet i:Alzheimers Dement
Main Authors: Hansson, Oskar, Seibyl, John, Stomrud, Erik, Zetterberg, Henrik, Trojanowski, John Q., Bittner, Tobias, Lifke, Valeria, Corradini, Veronika, Eichenlaub, Udo, Batrla, Richard, Buck, Katharina, Zink, Katharina, Rabe, Christina, Blennow, Kaj, Shaw, Leslie M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119541/
https://ncbi.nlm.nih.gov/pubmed/29499171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.01.010
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