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Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retina

Mutations in the epithelial polarity gene crumbs (crb) lead to retinal degeneration in Drosophila and in humans. The overall morphology of the retina and its deterioration in Drosophila crb mutants has been well-characterized, but the cell biological origin of the degeneration is not well understood...

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Publicado en:PLoS One
Autores principales: Kraut, Rachel S., Knust, Elisabeth
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910688/
https://ncbi.nlm.nih.gov/pubmed/31834921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220220
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