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Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retina

Mutations in the epithelial polarity gene crumbs (crb) lead to retinal degeneration in Drosophila and in humans. The overall morphology of the retina and its deterioration in Drosophila crb mutants has been well-characterized, but the cell biological origin of the degeneration is not well understood...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kraut, Rachel S., Knust, Elisabeth
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910688/
https://ncbi.nlm.nih.gov/pubmed/31834921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220220
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