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Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retina

Mutations in the epithelial polarity gene crumbs (crb) lead to retinal degeneration in Drosophila and in humans. The overall morphology of the retina and its deterioration in Drosophila crb mutants has been well-characterized, but the cell biological origin of the degeneration is not well understood...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kraut, Rachel S., Knust, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910688/
https://ncbi.nlm.nih.gov/pubmed/31834921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220220
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