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Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila

The evolutionarily conserved Crumbs protein is required for epithelial polarity and morphogenesis. Here we identify a novel role of Crumbs as a negative regulator of actomyosin dynamics during dorsal closure in the Drosophila embryo. Embryos carrying a mutation in the FERM (protein 4.1/ezrin/radixin...

詳細記述

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書誌詳細
出版年:eLife
主要な著者: Flores-Benitez, David, Knust, Elisabeth
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718732/
https://ncbi.nlm.nih.gov/pubmed/26544546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07398
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