Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo using Layer-by-Layer Nanoparticles

Using siRNA therapeutics to treat hematologic malignancies has been unsuccessful because blood cancer cells exhibit remarkable resistance to standard transfection methods. Herein we report the successful delivery of siRNA therapeutics with a dual-targeted, layer-by-layer nanoparticle (LbL-NP). The L...

詳細記述

保存先:
書誌詳細
出版年:Adv Funct Mater
主要な著者: Choi, Ki Young, Correa, Santiago, Min, Jouha, Li, Jiahe, Roy, Sweta, Laccetti, Kristiana H, Dreaden, Erik, Kong, Stephanie, Heo, Roun, Roh, Young Hoon, Lawson, Edward C, Palmer, Peter A, Hammond, Paula T
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910249/
https://ncbi.nlm.nih.gov/pubmed/31839764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201900018
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