Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo using Layer-by-Layer Nanoparticles

Using siRNA therapeutics to treat hematologic malignancies has been unsuccessful because blood cancer cells exhibit remarkable resistance to standard transfection methods. Herein we report the successful delivery of siRNA therapeutics with a dual-targeted, layer-by-layer nanoparticle (LbL-NP). The L...

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Bibliografiske detaljer
Udgivet i:Adv Funct Mater
Main Authors: Choi, Ki Young, Correa, Santiago, Min, Jouha, Li, Jiahe, Roy, Sweta, Laccetti, Kristiana H, Dreaden, Erik, Kong, Stephanie, Heo, Roun, Roh, Young Hoon, Lawson, Edward C, Palmer, Peter A, Hammond, Paula T
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910249/
https://ncbi.nlm.nih.gov/pubmed/31839764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201900018
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