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Spexin alleviates insulin resistance and inhibits hepatic gluconeogenesis via the FoxO1/PGC-1α pathway in high-fat-diet-induced rats and insulin resistant cells
Objective: Recent studies demonstrate circulating serum spexin levels are reduced in obesity or type 2 diabetes mellitus (T2DM) patients and may play a role in glucose metabolism. The mechanism underlying is not known. In this study, we explore whether spexin has a role in insulin resistance and hep...
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Опубликовано в: : | Int J Biol Sci |
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Главные авторы: | , , , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Ivyspring International Publisher
2019
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6909969/ https://ncbi.nlm.nih.gov/pubmed/31853220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.31781 |
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