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Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen

Acute myelogenous leukemia (AML) is a hematological malignancy marked by the accumulation of large numbers of immature myeloblasts in bone marrow. The overall prognosis in AML is poor; hence, there is a pressing need to improve treatment. Although the sphingolipid (SL) ceramide demonstrates known ca...

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Dettagli Bibliografici
Pubblicato in:Exp Cell Res
Autori principali: Morad, Samy A.F., MacDougall, Matthew R., Abdelmageed, Noha, Kao, Li-Pin, Feith, David J., Tan, Su-Fern, Kester, Mark, Loughran, Thomas P., Wang, Hong-Gang, Cabot, Myles C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909922/
https://ncbi.nlm.nih.gov/pubmed/31112736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.05.021
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