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Missing tumor measurement (TM) data in the search for alternative TM-based endpoints in cancer clinical trials

PURPOSE: Missing data commonly occur in cancer clinical trials (CCT) and may hinder the search for alternative trial endpoints. We consider reasons for missing tumor measurement (TM) data in CCT and how missing TM data are typically handled. We explore the potential impact of missing TM data on pred...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials Commun
Main Authors: An, Ming-Wen, Tang, Jun, Grothey, Axel, Sargent, Daniel J., Ou, Fang-Shu, Mandrekar, Sumithra J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909186/
https://ncbi.nlm.nih.gov/pubmed/31872158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100492
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