MTA3 Represses Cancer Stemness by Targeting the SOX2OT/SOX2 Axis

Cancer cell stemness (CCS) plays critical roles in both malignancy maintenance and metastasis, yet the underlying molecular mechanisms are far from complete. Although the importance of SOX2 in cancer development and CCS are well recognized, the role of MTA3 in these processes is unknown. In this stu...

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Veröffentlicht in:iScience
Hauptverfasser: Du, Liang, Wang, Lu, Gan, Jinfeng, Yao, Zhimeng, Lin, Wan, Li, Junkuo, Guo, Yi, Chen, Yuping, Zhou, Fuyou, Jim Yeung, Sai-Ching, Coppes, Robert P., Zhang, Dianzheng, Zhang, Hao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909183/
https://ncbi.nlm.nih.gov/pubmed/31810000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.11.009
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