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Bax expression is optimal at low oxygen tension and constant agitation

Bax is a pro-apoptosis protein that translocates from the cytosol to the mitochondria membrane upon initiation of programed cell death. Bax subsequently disrupts the mitochondria membrane, resulting in the release of cytochrome C which activates the downstream caspases. The structure of inactive Bax...

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Bibliografiske detaljer
Udgivet i:Protein Expr Purif
Main Authors: He, Yi, Chen, Yong, Morris, Daniel L., Lee, Duck-Yeon, Tjandra, Nico
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908824/
https://ncbi.nlm.nih.gov/pubmed/31542563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2019.105501
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