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The Role of Human CD46 in Early Xenoislet Engraftment in a Dual Transplant Model

BACKGROUND: Membrane cofactor protein CD46 attenuates the complement cascade by facilitating cleavage of C3b and C4b. In solid organ xenotransplantation, organs expressing CD46 have been shown to resist hyperacute rejection. However, the incremental value of human CD46 expression for islet xenotrans...

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Bibliografski detalji
Izdano u:Xenotransplantation
Glavni autori: Samy, KP, Gao, Q, Davis, RP, Song, M, Fitch, ZW, Mulvihill, MS, MacDonald, A, Leopardi, FV, How, T, Williams, KD, Devi, GR, Collins, BH, Luo, X, Kirk, AD
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908747/
https://ncbi.nlm.nih.gov/pubmed/31219218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12540
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