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The Role of Human CD46 in Early Xenoislet Engraftment in a Dual Transplant Model

BACKGROUND: Membrane cofactor protein CD46 attenuates the complement cascade by facilitating cleavage of C3b and C4b. In solid organ xenotransplantation, organs expressing CD46 have been shown to resist hyperacute rejection. However, the incremental value of human CD46 expression for islet xenotrans...

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Detaylı Bibliyografya
Yayımlandı:Xenotransplantation
Asıl Yazarlar: Samy, KP, Gao, Q, Davis, RP, Song, M, Fitch, ZW, Mulvihill, MS, MacDonald, A, Leopardi, FV, How, T, Williams, KD, Devi, GR, Collins, BH, Luo, X, Kirk, AD
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908747/
https://ncbi.nlm.nih.gov/pubmed/31219218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12540
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