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A model of DNA damage response activation at stalled replication forks by SPRTN
The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6908633/ https://ncbi.nlm.nih.gov/pubmed/31831745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13610-7 |
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