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3β, 6β-dichloro-5-hydroxy-5α-cholestane facilitates neuronal development through modulating TrkA signaling regulated proteins in primary hippocampal neuron

Potentiating neuritogenesis through pharmacological intervention might hold therapeutic promise in neurodegenerative disorders and acute brain injury. Here, we investigated the novel neuritogenic potentials of a steroidal chlorohydrin, 3β, 6β-dichloro-5-hydroxy-5α-cholestane (hereafter, SCH) and the...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Hannan, Md. Abdul, Haque, Md. Nazmul, Dash, Raju, Alam, Mahboob, Moon, Il Soo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908615/
https://ncbi.nlm.nih.gov/pubmed/31831796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55364-8
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