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3β, 6β-dichloro-5-hydroxy-5α-cholestane facilitates neuronal development through modulating TrkA signaling regulated proteins in primary hippocampal neuron

Potentiating neuritogenesis through pharmacological intervention might hold therapeutic promise in neurodegenerative disorders and acute brain injury. Here, we investigated the novel neuritogenic potentials of a steroidal chlorohydrin, 3β, 6β-dichloro-5-hydroxy-5α-cholestane (hereafter, SCH) and the...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Hannan, Md. Abdul, Haque, Md. Nazmul, Dash, Raju, Alam, Mahboob, Moon, Il Soo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908615/
https://ncbi.nlm.nih.gov/pubmed/31831796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55364-8
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