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3β, 6β-dichloro-5-hydroxy-5α-cholestane facilitates neuronal development through modulating TrkA signaling regulated proteins in primary hippocampal neuron

Potentiating neuritogenesis through pharmacological intervention might hold therapeutic promise in neurodegenerative disorders and acute brain injury. Here, we investigated the novel neuritogenic potentials of a steroidal chlorohydrin, 3β, 6β-dichloro-5-hydroxy-5α-cholestane (hereafter, SCH) and the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hannan, Md. Abdul, Haque, Md. Nazmul, Dash, Raju, Alam, Mahboob, Moon, Il Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908615/
https://ncbi.nlm.nih.gov/pubmed/31831796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55364-8
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