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One-step artificial antigen presenting cell-based vaccines induce potent effector CD8 T cell responses

The production and wide use of artificial antigen presenting cells (aAPCs) in the clinic as cancer immunotherapeutics are hindered by the need of identifying immunogenic cancer antigens and production of recombinant patient-specific major histocompatibility complexes (MHC) loaded with these peptides...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Su, Qingtai, Igyártó, Botond Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908577/
https://ncbi.nlm.nih.gov/pubmed/31831802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55286-5
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