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One-step artificial antigen presenting cell-based vaccines induce potent effector CD8 T cell responses

The production and wide use of artificial antigen presenting cells (aAPCs) in the clinic as cancer immunotherapeutics are hindered by the need of identifying immunogenic cancer antigens and production of recombinant patient-specific major histocompatibility complexes (MHC) loaded with these peptides...

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Pubblicato in:Sci Rep
Autori principali: Su, Qingtai, Igyártó, Botond Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908577/
https://ncbi.nlm.nih.gov/pubmed/31831802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55286-5
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