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Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation

Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several human cancers, such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). Current treatment options for KSHV infection and virus associated diseases are sometimes ineffective, therefore, more effectively antiviral agents are urgen...

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Podrobná bibliografie
Vydáno v:PLoS Pathog
Hlavní autoři: Chen, Jungang, Dai, Lu, Goldstein, Alana, Zhang, Haiwei, Tang, Wei, Forrest, J. Craig, Post, Steven R., Chen, Xulin, Qin, Zhiqiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907871/
https://ncbi.nlm.nih.gov/pubmed/31790497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008156
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