Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation

Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several human cancers, such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). Current treatment options for KSHV infection and virus associated diseases are sometimes ineffective, therefore, more effectively antiviral agents are urgen...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chen, Jungang, Dai, Lu, Goldstein, Alana, Zhang, Haiwei, Tang, Wei, Forrest, J. Craig, Post, Steven R., Chen, Xulin, Qin, Zhiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907871/
https://ncbi.nlm.nih.gov/pubmed/31790497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008156
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