Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation

Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several human cancers, such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). Current treatment options for KSHV infection and virus associated diseases are sometimes ineffective, therefore, more effectively antiviral agents are urgen...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Chen, Jungang, Dai, Lu, Goldstein, Alana, Zhang, Haiwei, Tang, Wei, Forrest, J. Craig, Post, Steven R., Chen, Xulin, Qin, Zhiqiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907871/
https://ncbi.nlm.nih.gov/pubmed/31790497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008156
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