Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells

Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-α) are believed to play an important role in human immunodeficiency virus, type I (HIV-1) pathogenesis. PDCs produce IFN-α and other proinflammatory cytokines through stimulation of Toll-like receptor 7 (TLR7) and TLR9...

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Pubblicato in:PLoS One
Autori principali: Patamawenu, Andy A., Wright, Nathaniel E., Shofner, Tulley, Evans, Sean, Manion, Maura M., Doria-Rose, Nicole, Migueles, Stephen A., Mendoza, Daniel, Peterson, Bennett, Wilhelm, Christopher, Rood, Julia, Berkley, Amy, Cogliano, Nancy A., Liang, C. Jason, Tesselaar, Kiki, Miedema, Frank, Bess, Julian, Lifson, Jeffrey, Connors, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907767/
https://ncbi.nlm.nih.gov/pubmed/31830058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225806
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