Activation of natural killer cells by rituximab in granulomatosis with polyangiitis

OBJECTIVE: In the last few years, anti-CD20 antibody rituximab profoundly changed the therapeutic landscape of granulomatosis with polyangiitis (GPA). Here, we investigated whether natural killer (NK) cells may play a role in rituximab’s mechanism of action in GPA. METHODS: B cell depletion, NK cell...

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Bibliografische gegevens
Gepubliceerd in:Arthritis Res Ther
Hoofdauteurs: Urlaub, Doris, Zhao, Shuyang, Blank, Norbert, Bergner, Raoul, Claus, Maren, Tretter, Theresa, Lorenz, Hanns-Martin, Watzl, Carsten, Merkt, Wolfgang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907269/
https://ncbi.nlm.nih.gov/pubmed/31829278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-2054-0
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