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Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56(dim) natural killer cells

BACKGROUND: The role of natural killer (NK) cells in granulomatosis with polyangiitis (GPA) is poorly understood. We recently reported that peripheral blood NK cell percentages correlate with the suppression of GPA activity (cohort I). The purpose of the current study was to further characterize NK...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Merkt, Wolfgang, Claus, Maren, Blank, Norbert, Hundemer, Michael, Cerwenka, Adelheid, Lorenz, Hanns-Martin, Watzl, Carsten
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022237/
https://ncbi.nlm.nih.gov/pubmed/27624647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1098-7
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