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Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting

BACKGROUND: Rituximab has broad and increasing application in rheumatic diseases. It is known from lymphoma studies that natural killer (NK) cells can lyse rituximab-coated transformed B cells. However, the role of NK cells in mediating rituximab-induced depletion of non-malignant B cells is unknown...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Merkt, Wolfgang, Lorenz, Hanns-Martin, Watzl, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024429/
https://ncbi.nlm.nih.gov/pubmed/27629249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1101-3
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