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β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity

Although it is well established that type 2 diabetes (T2D) is generally due to the progressive loss of β-cell insulin secretion against a background of insulin resistance, the actual correlation of reduced β-cell mass to its defective function continues to be debated. There is evidence that a compen...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Mezza, Teresa, Cinti, Francesca, Cefalo, Chiara Maria Assunta, Pontecorvi, Alfredo, Kulkarni, Rohit N., Giaccari, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905483/
https://ncbi.nlm.nih.gov/pubmed/31109941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0856
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