Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery

BACKGROUND: The objectives of the study were to characterize and quantify cellular inflammation and structural remodeling of human atria and correlate findings with molecular markers of inflammation and patient surrogate outcome. METHODS: Voluntary participants undergoing heart surgery were enrolled...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Aguiar, Christie M., Gawdat, Kareem, Legere, Stephanie, Marshall, Jean, Hassan, Ansar, Kienesberger, Petra C., Pulinilkunnil, Thomas, Castonguay, Mathieu, Brunt, Keith R., Legare, Jean-Francois
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905054/
https://ncbi.nlm.nih.gov/pubmed/31822289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02162-5
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