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Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery

BACKGROUND: The objectives of the study were to characterize and quantify cellular inflammation and structural remodeling of human atria and correlate findings with molecular markers of inflammation and patient surrogate outcome. METHODS: Voluntary participants undergoing heart surgery were enrolled...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Aguiar, Christie M., Gawdat, Kareem, Legere, Stephanie, Marshall, Jean, Hassan, Ansar, Kienesberger, Petra C., Pulinilkunnil, Thomas, Castonguay, Mathieu, Brunt, Keith R., Legare, Jean-Francois
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905054/
https://ncbi.nlm.nih.gov/pubmed/31822289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02162-5
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