Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery

BACKGROUND: The objectives of the study were to characterize and quantify cellular inflammation and structural remodeling of human atria and correlate findings with molecular markers of inflammation and patient surrogate outcome. METHODS: Voluntary participants undergoing heart surgery were enrolled...

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Udgivet i:J Transl Med
Main Authors: Aguiar, Christie M., Gawdat, Kareem, Legere, Stephanie, Marshall, Jean, Hassan, Ansar, Kienesberger, Petra C., Pulinilkunnil, Thomas, Castonguay, Mathieu, Brunt, Keith R., Legare, Jean-Francois
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905054/
https://ncbi.nlm.nih.gov/pubmed/31822289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02162-5
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