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Human telomerase reverse transcriptase regulation by DNA methylation, transcription factor binding and alternative splicing (Review)
The catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), plays an essential role in telomere maintenance to oppose cellular senescence and, is highly regulated in normal and cancerous cells. Regulation of hTERT occurs through multiple avenues, including a unique pattern o...
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| Udgivet i: | Int J Oncol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6903903/ https://ncbi.nlm.nih.gov/pubmed/27779655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3743 |
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