Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function

Podocytes are key cells in maintaining the integrity of the glomerular filtration barrier and preventing albuminuria. Glycogen synthase kinase 3 (GSK3) is a multi‐functional serine/threonine kinase existing as two distinct but related isoforms (α and β). In the podocyte it has previously been report...

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Veröffentlicht in:FASEB Bioadv
Hauptverfasser: Hurcombe, Jennifer A., Lay, Abigail C., Ni, Lan, Barrington, Alexandra F., Woodgett, Jim R., Quaggin, Susan E., Welsh, Gavin I., Coward, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902909/
https://ncbi.nlm.nih.gov/pubmed/31825015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00011
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