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Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function

Podocytes are key cells in maintaining the integrity of the glomerular filtration barrier and preventing albuminuria. Glycogen synthase kinase 3 (GSK3) is a multi‐functional serine/threonine kinase existing as two distinct but related isoforms (α and β). In the podocyte it has previously been report...

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Detalhes bibliográficos
Publicado no:FASEB Bioadv
Main Authors: Hurcombe, Jennifer A., Lay, Abigail C., Ni, Lan, Barrington, Alexandra F., Woodgett, Jim R., Quaggin, Susan E., Welsh, Gavin I., Coward, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902909/
https://ncbi.nlm.nih.gov/pubmed/31825015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00011
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