Coenzyme Q(10) alleviates tacrolimus-induced mitochondrial dysfunction in kidney

The major side effect of tacrolimus (Tac) is nephrotoxicity. We studied whether supplementation of coenzyme Q(10), (CoQ(10)) a potent antioxidant, can reduce Tac-induced nephrotoxicity via improving mitochondrial function. In an in vitro study, CoQ(10) reduced the production of Tac-induced mitochond...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Yu, Ji Hyun, Lim, Sun Woo, Luo, Kang, Cui, Sheng, Quan, Yi, Shin, Yoo Jin, Lee, Kyung Eun, Kim, Hong Lim, Ko, Eun Jeong, Chung, Byung Ha, Kim, Ju Hwan, Chung, Sang J., Yang, Chul Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902707/
https://ncbi.nlm.nih.gov/pubmed/31431058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900386RR
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