Ginseng increases Klotho expression by FoxO3-mediated manganese superoxide dismutase in a mouse model of tacrolimus-induced renal injury

The antioxidant function of Klotho is well-documented as a regulatory factor implicated in countering the aging process. This study investigated whether ginseng upregulates Klotho and its antiaging signaling in a setting of calcineurin inhibitor-induced oxidative stress. Although tacrolimus treatmen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging (Albany NY)
Prif Awduron: Lim, Sun Woo, Shin, Yoo Jin, Luo, Kang, Quan, Yi, Cui, Sheng, Ko, Eun Jeong, Chung, Byung Ha, Yang, Chul Woo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710054/
https://ncbi.nlm.nih.gov/pubmed/31400753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102137
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