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Heterochronic regulation of lung development via the Lin28–Let-7 pathway

The heterochronic gene Lin28 regulates diverse developmental processes. It was shown previously that global Lin28A overexpression during mouse embryogenesis results in perinatal lethality. However, the reason for this early lethality has not been elucidated. Here, we showed that Lin28A overexpressio...

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Bibliographic Details
Published in:FASEB J
Main Authors: Komarovsky Gulman, Nelly, Armon, Leah, Shalit, Tali, Urbach, Achia
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902705/
https://ncbi.nlm.nih.gov/pubmed/31373834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802702R
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