LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7

The RNA-binding proteins LIN28A and LIN28B have diverse functions in embryonic stem cells, cellular reprogramming, growth, and oncogenesis. Many of these effects occur via direct inhibition of Let-7 microRNAs (miRNAs), although Let-7-independent effects have been surmised. We report that intestine t...

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Main Authors: Madison, Blair B., Liu, Qi, Zhong, Xue, Hahn, Christopher M., Lin, Nan, Emmett, Matthew J., Stanger, Ben Z., Lee, Ju-Seog, Rustgi, Anil K.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2013
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814644/
https://ncbi.nlm.nih.gov/pubmed/24142874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.224659.113
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