Nalaganje...
LIN28B fosters colon cancer migration, invasion, and transformation through let-7 dependent and independent mechanisms
Lin28b is an RNA-binding protein that inhibits biogenesis of let-7 microRNAs. LIN28B is overexpressed in diverse cancers, yet a specific role in the molecular pathogenesis of colon cancer has yet to be elucidated. We have determined that human colon tumors exhibit decreased levels of mature let-7 is...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3165068/ https://ncbi.nlm.nih.gov/pubmed/21625210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.131 |
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