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Lin28b promotes colon cancer progression and metastasis

LIN28B is a homolog of LIN28 which induces pluripotency when expressed in conjunction with OCT4, SOX2, and KLF4 in somatic fibroblasts. LIN28B represses biogenesis of let-7 microRNAs and is implicated in both development and tumorigenesis. Recently, we have determined that LIN28B overexpression occu...

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Hlavní autoři: King, Catrina, Cuatrecasas, Miriam, Castells, Antoni, Sepulveda, Antonia, Lee, Ju-Seog, Rustgi, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117110/
https://ncbi.nlm.nih.gov/pubmed/21512136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4637
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