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Lin28b promotes colon cancer progression and metastasis
LIN28B is a homolog of LIN28 which induces pluripotency when expressed in conjunction with OCT4, SOX2, and KLF4 in somatic fibroblasts. LIN28B represses biogenesis of let-7 microRNAs and is implicated in both development and tumorigenesis. Recently, we have determined that LIN28B overexpression occu...
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Autors principals: | , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2011
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117110/ https://ncbi.nlm.nih.gov/pubmed/21512136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4637 |
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