Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion

Invasive spread of glioblastoma (GBM) is linked to changes in chondroitin sulfate (CS) proteoglycan (CSPG)–associated sulfated glycosaminoglycans (GAGs) that are selectively up-regulated in the tumor microenvironment (TME). We hypothesized that inhibiting CS-GAG signaling in the TME would stem GBM i...

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Bibliografiska uppgifter
I publikationen:FASEB J
Huvudupphovsmän: Logun, Meghan T., Wynens, Kallie E., Simchick, Gregory, Zhao, Wujun, Mao, Leidong, Zhao, Qun, Mukherjee, Subhas, Brat, Daniel J., Karumbaiah, Lohitash
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902699/
https://ncbi.nlm.nih.gov/pubmed/31398290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802610RR
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